Laboratory Drug Testing Across South Dakota

Order a Drug Test in South Dakota

Need a drug test in South Dakota? Individuals and employers can order a laboratory urine drug test online for employment, personal, or other non-DOT needs. Choose a panel, create the testing case, and then select an available collection site during checkout for areas including Sioux Falls, Rapid City, Aberdeen, Brookings, Watertown, Mitchell, and surrounding communities.

Drug Tests Available in South Dakota

Review the substances included in each panel, then choose Order This Test to open the order page with that panel already selected.

Includes THC

5 Panel Drug Test

Laboratory urine drug test.

Comprehensive screening panel including marijuana/THC.

View Drugs Included
This panel tests for:
  • Amphetamines
  • Cocaine
  • Ext. Opiates
  • Marijuana
  • MDA-Analogues
  • Opiates
  • Oxycodones
  • Phencyclidine (PCP)
Order This Test →
No THC

4 Panel Drug Test

Laboratory urine drug test.

Expanded opiates panel without marijuana/THC.

View Drugs Included
This panel tests for:
  • Amphetamines
  • Cocaine
  • MDA-Analogues
  • Opiates
  • Oxycodones
  • Phencyclidine (PCP)
Order This Test →
Comprehensive

10 Panel Drug Test

Laboratory urine drug test.

Broad screening across commonly tested drug classes.

View Drugs Included
This panel tests for:
  • Amphetamines
  • Barbiturates
  • Benzodiazepines
  • Cocaine
  • Marijuana
  • MDA-Analogues
  • Methadone
  • Methaqualone
  • Opiates
  • Phencyclidine (PCP)
  • Propoxyphene
Order This Test →
No THC

9 Panel Drug Test

Laboratory urine drug test.

Comprehensive screening panel without marijuana/THC.

View Drugs Included
This panel tests for:
  • Amphetamines
  • Barbiturates
  • Benzodiazepines
  • Cocaine
  • Methadone
  • Methaqualone
  • Opiates
  • Phencyclidine (PCP)
  • Propoxyphene
Order This Test →
Drug + Alcohol

11 Panel Drug Test + Alcohol

Laboratory urine drug test.

Comprehensive drug screening with urine alcohol testing.

View Drugs Included
This panel tests for:
  • Alcohol (Urine)
  • Amphetamines
  • Barbiturates
  • Benzodiazepines
  • Cocaine
  • Marijuana
  • Methadone
  • Methaqualone
  • Opiates
  • Phencyclidine (PCP)
  • Propoxyphene
Order This Test →
South Dakota employers: Private employers generally have flexibility to establish lawful testing programs, but registered medical-cannabis patients receive employment-related protections. Before acting on a cannabis result, identify whether the job is safety-sensitive under state law and account for any federal, contract, or collective-bargaining requirements.

How to Order a Drug Test in South Dakota

If you searched for a “drug test near me” in South Dakota, start by creating your order. Once the case is created, the ordering process can search available collection sites using your city, ZIP code, or other location information. Live collection-site availability is shown only after the testing case exists.

1

Choose Your Test

Select the urine drug-testing panel that fits your needs.

2

Enter Donor Information

Provide the information needed to create the electronic testing order.

3

Select a Collection Site

After the case is created, search the collection sites available for the South Dakota area you enter.

4

Get Your Donor Pass

Complete payment, receive your Donor Pass, and bring it with valid photo ID.

Important: Collection-site availability is shown during the ordering process after a case number is created. This page does not display or promise a specific collection site before an order exists.

Drug Testing Locations Across South Dakota

Start an order online from anywhere in South Dakota. After the testing case is created, the order process searches available collection sites based on the location entered by the customer.

South Dakota Cities and Counties

South Dakota testing demand spans health care, finance, education, government, agriculture, food processing, construction, manufacturing, transportation, tourism, hospitality, energy, utilities, and professional services. Collection-site availability is searched inside checkout after the testing case is created.

Sioux FallsRapid CityAberdeenBrookingsWatertownMitchellYanktonHuronPierreSpearfishBox ElderVermillionBrandonSturgisMadisonBelle FourcheHarrisburgTeaDell RapidsHot SpringsMinnehaha CountyPennington CountyLincoln CountyBrown CountyBrookings CountyCodington CountyLawrence CountyDavison CountyYankton CountyBeadle CountyMeade CountyHughes CountyUnion CountyClay County

Pre-Employment and Employer Drug Testing in South Dakota

South Dakota private employers generally may establish drug-testing programs when the policy and its administration are lawful. The state does not use one comprehensive statute to prescribe every private-sector test, but its medical-cannabis law creates important employment and drug-testing protections with a specific exception for safety-sensitive jobs. Unemployment and workers’ compensation laws address separate consequences. DTC supports laboratory urine testing for lawful pre-employment, random, reasonable-suspicion, post-accident, return-to-duty, follow-up, and other authorized programs.

Pre-Employment Drug Testing in South Dakota

A private employer generally may make employment conditional on a negative drug test when the requirement is lawful, communicated clearly, and applied consistently to similarly situated applicants. The policy should identify covered positions, the panel, the timing of testing, and the consequences of a refusal or confirmed positive result. The employer should classify any safety-sensitive jobs before testing and establish a confidential process for reviewing registered qualifying-patient status.

  • Give clear advance notice of the testing requirement.
  • Use job-related, neutral criteria for covered positions.
  • Apply the same criteria to similarly situated applicants.
  • Use documented collection and chain-of-custody procedures.
  • Confirm non-negative screens at a professional certified laboratory.
  • Use Medical Review Officer review when appropriate.
  • Keep test and medical information confidential.
  • Document which jobs meet South Dakota’s safety-sensitive definition.
  • Apply medical-cannabis protections before acting on a cannabis result.
  • Review federal, discrimination, contract, and collective-bargaining rules.

Employer Testing Programs

A defensible program explains who is covered, substances tested, testing reasons, specimen and laboratory procedures, refusals, confirmation and review, employee opportunities to provide legitimate medical information, consequences, records, and confidentiality. Apply the written policy as drafted and revise it before changing program practice. For cannabis, the policy should distinguish safety-sensitive jobs from other positions and explain how registered qualifying-patient information will be reviewed.

  • Use a neutral selection process for any random program.
  • Train supervisors to document objective reasonable-suspicion facts.
  • Tie post-accident criteria to legitimate safety concerns.
  • Keep DOT and non-DOT programs, forms, and records separate.
  • State how refusals, adulteration, and substituted specimens are handled.
  • Use laboratory confirmation before treating a screen as positive.
  • Use consistent review and consequence procedures.
  • Limit disclosure to personnel with a business need to know.
  • Do not treat a cannabis-metabolite result as present-impairment evidence.

Select the panel and enter the donor information first. After the case is created, checkout searches available collection sites using the South Dakota city, ZIP code, or area entered for the donor.

Start a South Dakota drug-test order →

Need a pre-employment drug test in South Dakota? Choose the panel authorized by the employer’s policy, communicate the requirement consistently, and identify whether the position is safety-sensitive before acting on any cannabis result. Use documented collection, laboratory confirmation, appropriate review, and confidential records. Create the testing case first, then select an available collection site during checkout.

South Dakota Drug Testing Laws and Employer Rules

South Dakota does not use one comprehensive statute to prescribe every private-employer test. Employers must coordinate their policy with the state’s medical-cannabis employment protections, unemployment and workers’ compensation laws, plus any applicable federal, public-sector, discrimination, privacy, contract, licensing, or collective-bargaining requirements. This overview does not replace legal advice.

Private-Employer Framework

Private employers generally have room to use pre-employment and employee testing under a lawful policy. The absence of a single statewide testing code is not a license for arbitrary treatment: the testing reason, job coverage, selection method, panel, review, and consequences should be legitimate and consistently administered.

Government employers, union workplaces, federally regulated employers, and organizations operating under a contract, grant, or licensing rule may have additional limits or mandatory procedures.

Written Policy and Consistent Administration

A written policy should identify prohibited conduct, covered workers, testing reasons, collection and laboratory procedures, refusals, confirmation, medical review, retesting, consequences, confidentiality, and any assistance options.

SDCL 34-20G-24 expressly permits an employer to establish and enforce a drug-free workplace policy, including a testing program that complies with state and federal law. The same statute permits action under that lawful policy, but the policy still must be coordinated with the chapter’s registered-patient protections and safety-sensitive exception.

State law: SDCL 34-20G-24

Unemployment and Work-Connected Misconduct

SDCL 61-6-14 generally denies benefits to a person discharged or suspended from the person’s most recent employment of at least thirty calendar days for misconduct connected with work. The denial continues until the person is reemployed for at least six calendar weeks in insured employment during the current benefit year and earns at least the weekly benefit amount in each of those weeks. The thirty-day condition does not apply to an additional claim filed during the benefit year.

SDCL 61-6-14.1 defines misconduct through failures to obey rules or duties, substantial or willful disregard of the employer’s interests, and sufficiently culpable carelessness, while excluding inefficiency, inability, and good-faith errors. A deliberate drug-policy violation or refusal may support a misconduct finding when the evidence meets that definition, but neither statute makes every positive result or refusal automatically disqualifying.

State law: SDCL 61-6-14 and SDCL 61-6-14.1

Workers’ Compensation and Intoxication

SDCL 62-4-37 provides that no compensation may be allowed for an injury or death due to the employee’s willful misconduct, including intoxication, illegal use of a Schedule I or Schedule II drug, intentional self-injury, or a willful safety-related failure listed in the statute. The defendant employer bears the burden of proof.

Because the statute requires the injury or death to be “due to” the listed conduct, a positive result alone should not be described as automatically defeating a claim or proving causation.

State law: SDCL 62-4-37

Registered Patients and Safety-Sensitive Jobs

SDCL 34-20G-22 generally gives a registered qualifying patient using cannabis medically the same state and local law rights as a person solely prescribed a pharmaceutical medication for interactions with an employer and drug testing. SDCL 34-20G-23 limits those rights when they conflict with a federal obligation or would cause an employer to lose a federal monetary or licensing benefit.

For a safety-sensitive job, an employer may take adverse action against an employee or refuse to hire an applicant based solely on a positive test for cannabis metabolites. State law defines such a job by tasks or duties the employer reasonably believes could cause illness, injury, or death or serious property damage.

State law: SDCL 34-20G-22, 34-20G-23, and 34-20G-1

Federal, Government, and Contract Rules

DOT-covered transportation testing must follow 49 CFR Part 40 and the applicable agency rule. Federal contractors and grantees may have duties under the federal Drug-Free Workplace Act, and government testing may raise constitutional, civil-service, or other public-employment requirements.

Collective-bargaining agreements, licensing rules, client contracts, and industry-specific requirements can also determine whether, when, and how testing occurs. Keep any federally mandated process distinct from a general non-DOT program.

Federal source: U.S. DOT — 49 CFR Part 40

Use results for the purpose the policy supports. A confirmed laboratory result, proof of present impairment, an unemployment determination, and a workers’ compensation causation decision are different questions. Document the testing reason and follow the procedure applicable to that decision.

Cannabis and Workplace Drug Testing in South Dakota

South Dakota operates a regulated medical-cannabis program and gives registered qualifying patients specific employment and drug-testing protections. Those protections are not absolute: state law creates a safety-sensitive-job exception, preserves lawful drug-free workplace policies, and recognizes conflicts with federal obligations and benefits.

Registered Qualifying-Patient Rights

South Dakota’s Department of Health administers a medical-cannabis program for qualifying patients. Under SDCL 34-20G-22, a registered qualifying patient using cannabis for a medical purpose generally must receive the same rights under state and local law as a person solely prescribed a pharmaceutical medication for employer interactions, employer drug testing, and testing required by state or local government.

A card is not a blanket pass for every workplace circumstance. Employers should verify status through a confidential process, identify the law and policy applicable to the decision, and apply the safety-sensitive and federal exceptions accurately.

Official sources: South Dakota Department of Health — Medical Cannabis Program and SDCL 34-20G-22

Safety-Sensitive-Job Exception

A safety-sensitive job is any position with tasks or duties the employer reasonably believes could cause an individual’s illness, injury, or death or result in serious property damage. State law permits adverse action against a person employed in such a job based solely on a positive test for cannabis metabolites.

An employer may likewise refuse to hire an applicant seeking a safety-sensitive job based solely on that result. Because the exception depends on the work, employers should classify positions from actual tasks and document the reasonable safety basis before a test result arrives.

State law: SDCL 34-20G-1 and SDCL 34-20G-22

Drug-Free Workplace and On-Duty Conduct

Employers are not required to allow cannabis ingestion, possession, transfer, display, or transportation in the workplace or working under the influence. SDCL 34-20G-24 allows an employer to establish and enforce a drug-free workplace policy, including a testing program compliant with state and federal law, and SDCL 34-20G-28 permits discipline for workplace ingestion or working under the influence.

The policy should distinguish a laboratory metabolite result from observed conduct or present impairment. A urine cannabis result can reflect prior exposure and, by itself, does not show when use occurred or whether the person is currently under the influence.

State law: SDCL 34-20G-24 and SDCL 34-20G-28

Adult Use and Federal Requirements

South Dakota’s medical program does not authorize general adult-use marijuana possession; the state’s controlled-substance laws continue to prohibit nonmedical possession. Separately, SDCL 34-20G-23 limits registered-patient rights when they conflict with an employer’s federal obligation or would cause the employer to lose a federal monetary or licensing benefit.

DOT-regulated employers must follow federal marijuana-testing rules. Non-DOT employers should also review federal contracts, grants, licensing duties, disability law, and any collective-bargaining agreement before finalizing cannabis policy or taking action.

State law: SDCL 22-42-6 and SDCL 34-20G-23

Choose THC or no THC intentionally. A THC-inclusive test should match the written policy, registered-patient review process, and documented job classification. No-THC panels are available when a non-DOT employer intentionally excludes marijuana. DOT testing remains subject to federal rules and includes marijuana.

DOT Drug Testing in South Dakota

South Dakota employers with employees performing federally regulated safety-sensitive transportation functions must follow the applicable federal DOT rules. The core procedural rule is 49 CFR Part 40, together with the regulations of the applicable DOT agency.

DOT Rules Are Separate from Non-DOT Testing

A personal or employer non-DOT drug test should not be substituted for a test that is required under DOT regulations. DOT programs have specific requirements for test reasons, forms, collection procedures, laboratories, Medical Review Officers, refusals, records, and return-to-duty processes.

Federal source: U.S. Department of Transportation — 49 CFR Part 40

Examples of DOT-Regulated Industries

  • Commercial motor carriers regulated by FMCSA.
  • Aviation employers regulated by FAA.
  • Railroad employers regulated by FRA.
  • Public transit employers regulated by FTA.
  • Pipeline operators regulated by PHMSA.
  • Other covered transportation operations under federal rules.

Drug Use and Overdose Data in South Dakota

CDC final 2024 mortality data provides statewide context for employers, individuals, policymakers, and safety programs. Population-level data should never be used to make assumptions about a particular person, workplace, city, county, or community.

98Drug overdose deaths in South DakotaCDC final 2024 drug-overdose death count.
11.9Overdose death rate per 100,000CDC final 2024 age-adjusted drug-overdose mortality rate.

Official sources: CDC — Drug Overdose Mortality by State and CDC — South Dakota Stats of the States. All 2024 data shown by CDC on these pages is final.

South Dakota Drug Testing FAQ

Can private employers drug test applicants and employees in South Dakota?
Generally, yes. South Dakota does not have a single comprehensive statute prescribing every private-sector drug-test procedure. Employers should use lawful, written, job-related, consistently administered policies and account for medical-cannabis protections, safety-sensitive positions, federal rules, discrimination law, contracts, collective-bargaining agreements, and public-sector requirements.
Can South Dakota employers require pre-employment drug testing?
Generally, yes. A private employer may make a job offer conditional on a negative test when the requirement is lawful and applied consistently to similarly situated applicants. Before acting on a cannabis result, determine whether the applicant is a registered qualifying patient and whether the position meets South Dakota’s safety-sensitive-job definition. Clear notice, documented chain of custody, laboratory confirmation, Medical Review Officer review, and confidential handling are prudent.
Can South Dakota employers use random, reasonable-suspicion, or post-accident testing?
Generally, a private employer may use those testing reasons when a lawful written policy authorizes them. Random selections should be neutral, reasonable-suspicion decisions should be based on contemporaneous objective facts, and post-accident criteria should be tied to legitimate safety concerns. Medical-cannabis protections and the safety-sensitive-job exception must be considered before acting on a cannabis result.
Does South Dakota require a written drug-testing policy?
No single statewide law expressly requires every private employer to maintain one for every non-DOT test. However, SDCL 34-20G-24 expressly permits an employer to establish and enforce a drug-free workplace policy, including a testing program that complies with state and federal law. A written policy is essential for notice, consistent administration, and documented cannabis and safety-sensitive-job decisions.
Can a positive drug test or refusal affect unemployment benefits in South Dakota?
Potentially. Under SDCL 61-6-14 and 61-6-14.1, discharge or suspension for misconduct connected with work can cause a benefits denial until the claimant completes the statute’s reemployment and earnings requirements. A deliberate drug-policy violation or refusal may support misconduct if the facts meet the statutory definition, but the statutes do not make every positive result or refusal an automatic disqualification.
Can intoxication affect South Dakota workers’ compensation benefits?
Potentially. SDCL 62-4-37 bars compensation for an injury or death due to willful misconduct, including intoxication or illegal use of a Schedule I or Schedule II drug. The employer bears the burden of proof, and a positive test alone should not be described as automatically proving that the injury or death was due to the listed conduct.
Does a South Dakota medical-cannabis card protect an applicant or employee?
Yes, but the protection is not absolute. SDCL 34-20G-22 generally affords a registered qualifying patient the same state and local law rights as a person solely prescribed a pharmaceutical medication for employer interactions and drug testing. Exceptions include safety-sensitive jobs and circumstances involving federal obligations or federal monetary or licensing benefits.
What is South Dakota’s safety-sensitive-job exception?
A safety-sensitive job is one with tasks or duties the employer reasonably believes could cause illness, injury, or death or serious property damage. For such a job, South Dakota law permits adverse action against an employee, or refusal to hire an applicant, based solely on a positive test for cannabis metabolites. Employers should classify and document these positions carefully.
Are DOT drug tests in South Dakota different from non-DOT tests?
Yes. DOT-regulated testing follows federal requirements, including 49 CFR Part 40. A personal or non-DOT employer test cannot replace a federally required DOT test.
What should I bring to a urine drug test in South Dakota?
Bring a valid photo ID and the Donor Pass issued for your order. Collection-site instructions and availability are shown during the ordering process after the case is created.
How long do urine drug-test results usually take?
Many negative laboratory urine results are available within roughly 1–2 business days after laboratory receipt. Confirmation or Medical Review Officer review can add several business days.

South Dakota and Federal Drug Testing Resources

We prioritize primary government sources for legal and public-health information and supplement them where useful. We periodically review this page for changes.

Ready to Order a Drug Test in South Dakota?

Choose your laboratory urine drug test, create the order, select an available collection site during checkout, and receive your Donor Pass.

This page is provided for general informational purposes and is not legal or medical advice. Drug-testing requirements can vary based on employer type, testing reason, industry, government status, collective-bargaining obligations, contracts, and federal or local requirements. Employers should consult qualified counsel before adopting or changing a testing policy. Public-health statistics are population-level estimates and should not be used to make assumptions about any individual or community.