Laboratory Drug Testing Across South Carolina

Order a Drug Test in South Carolina

Need a drug test in South Carolina? Individuals and employers can order a laboratory urine drug test online for employment, personal, or other non-DOT needs. Choose a panel, create the testing case, and then select an available collection site during checkout for areas including Charleston, Columbia, Greenville, Rock Hill, Spartanburg, Myrtle Beach, and surrounding communities.

Drug Tests Available in South Carolina

Review the substances included in each panel, then choose Order This Test to open the order page with that panel already selected.

Includes THC

5 Panel Drug Test

Laboratory urine drug test.

Comprehensive screening panel including marijuana/THC.

View Drugs Included
This panel tests for:
  • Amphetamines
  • Cocaine
  • Ext. Opiates
  • Marijuana
  • MDA-Analogues
  • Opiates
  • Oxycodones
  • Phencyclidine (PCP)
Order This Test →
No THC

4 Panel Drug Test

Laboratory urine drug test.

Expanded opiates panel without marijuana/THC.

View Drugs Included
This panel tests for:
  • Amphetamines
  • Cocaine
  • MDA-Analogues
  • Opiates
  • Oxycodones
  • Phencyclidine (PCP)
Order This Test →
Comprehensive

10 Panel Drug Test

Laboratory urine drug test.

Broad screening across commonly tested drug classes.

View Drugs Included
This panel tests for:
  • Amphetamines
  • Barbiturates
  • Benzodiazepines
  • Cocaine
  • Marijuana
  • MDA-Analogues
  • Methadone
  • Methaqualone
  • Opiates
  • Phencyclidine (PCP)
  • Propoxyphene
Order This Test →
No THC

9 Panel Drug Test

Laboratory urine drug test.

Comprehensive screening panel without marijuana/THC.

View Drugs Included
This panel tests for:
  • Amphetamines
  • Barbiturates
  • Benzodiazepines
  • Cocaine
  • Methadone
  • Methaqualone
  • Opiates
  • Phencyclidine (PCP)
  • Propoxyphene
Order This Test →
Drug + Alcohol

11 Panel Drug Test + Alcohol

Laboratory urine drug test.

Comprehensive drug screening with urine alcohol testing.

View Drugs Included
This panel tests for:
  • Alcohol (Urine)
  • Amphetamines
  • Barbiturates
  • Benzodiazepines
  • Cocaine
  • Marijuana
  • Methadone
  • Methaqualone
  • Opiates
  • Phencyclidine (PCP)
  • Propoxyphene
Order This Test →
South Carolina employers: Private employers generally have flexibility to establish lawful testing programs, but a written, consistently applied policy remains essential. South Carolina’s unemployment statute uses specific collection, laboratory, and confirmation standards, covered state contractors have separate drug-free-workplace duties, and federal or collective-bargaining rules may also control.

How to Order a Drug Test in South Carolina

If you searched for a “drug test near me” in South Carolina, start by creating your order. Once the case is created, the ordering process can search available collection sites using your city, ZIP code, or other location information. Live collection-site availability is shown only after the testing case exists.

1

Choose Your Test

Select the urine drug-testing panel that fits your needs.

2

Enter Donor Information

Provide the information needed to create the electronic testing order.

3

Select a Collection Site

After the case is created, search the collection sites available for the South Carolina area you enter.

4

Get Your Donor Pass

Complete payment, receive your Donor Pass, and bring it with valid photo ID.

Important: Collection-site availability is shown during the ordering process after a case number is created. This page does not display or promise a specific collection site before an order exists.

Drug Testing Locations Across South Carolina

Start an order online from anywhere in South Carolina. After the testing case is created, the order process searches available collection sites based on the location entered by the customer.

South Carolina Cities and Counties

South Carolina testing demand spans advanced manufacturing, aerospace, automotive production, health care, education, government, ports and maritime trades, construction, logistics, tourism, hospitality, agriculture, utilities, and professional services. Collection-site availability is searched inside checkout after the testing case is created.

Charleston Columbia North Charleston Mount Pleasant Rock Hill Greenville Summerville Goose Creek Sumter Florence Spartanburg Hilton Head Island Myrtle Beach Greer Aiken Anderson Greenwood Bluffton Beaufort Orangeburg Greenville County Richland County Charleston County Horry County Spartanburg County Lexington County York County Berkeley County Anderson County Beaufort County Aiken County Dorchester County Florence County Pickens County

Pre-Employment and Employer Drug Testing in South Carolina

South Carolina private employers generally may establish drug-testing programs when the policy and its administration are lawful. Unlike states with a comprehensive private-sector testing statute, South Carolina addresses particular consequences and employer categories through laws such as its unemployment, workers’ compensation, and Drug-Free Workplace Act provisions. DTC supports laboratory urine testing for lawful pre-employment, random, reasonable-suspicion, post-accident, return-to-duty, follow-up, and other authorized programs.

Pre-Employment Drug Testing in South Carolina

A private employer generally may make employment conditional on a negative drug test when the requirement is lawful, communicated clearly, and applied consistently to similarly situated applicants. The policy should identify covered positions, the panel, the timing of testing, and the consequences of a refusal or confirmed positive result.

  • Give clear advance notice of the testing requirement.
  • Use job-related, neutral criteria for covered positions.
  • Apply the same criteria to similarly situated applicants.
  • Use documented collection and chain-of-custody procedures.
  • Confirm non-negative screens at a professional certified laboratory.
  • Use Medical Review Officer review when appropriate.
  • Keep test and medical information confidential.
  • Review federal, discrimination, contract, and collective-bargaining rules.

Employer Testing Programs

A defensible program explains who is covered, substances tested, testing reasons, specimen and laboratory procedures, refusals, confirmation and review, employee opportunities to provide legitimate medical information, consequences, records, and confidentiality. Apply the written policy as drafted and revise it before changing program practice.

  • Use a neutral selection process for any random program.
  • Train supervisors to document objective reasonable-suspicion facts.
  • Tie post-accident criteria to legitimate safety concerns.
  • Keep DOT and non-DOT programs, forms, and records separate.
  • State how refusals, adulteration, and substituted specimens are handled.
  • Use laboratory confirmation before treating a screen as positive.
  • Use consistent review and consequence procedures.
  • Limit disclosure to personnel with a business need to know.

Select the panel and enter the donor information first. After the case is created, checkout searches available collection sites using the South Carolina city, ZIP code, or area entered for the donor.

Start a South Carolina drug-test order →

Need a pre-employment drug test in South Carolina? Choose the panel authorized by the employer’s policy, communicate the requirement consistently, and use documented collection, laboratory confirmation, appropriate review, and confidential records. Create the testing case first, then select an available collection site during checkout.

South Carolina Drug Testing Laws and Employer Rules

South Carolina does not use one comprehensive statute to prescribe every private-employer test. Instead, employers must coordinate their policy with specific state laws governing unemployment claims, workers’ compensation, covered state contracts and grants, and controlled substances, plus any applicable federal, public-sector, discrimination, privacy, contract, or collective-bargaining requirements. This overview does not replace legal advice.

Private-Employer Framework

Private employers generally have room to use pre-employment and employee testing under a lawful policy. The absence of a single statewide testing code is not a license for arbitrary treatment: the testing reason, job coverage, selection method, panel, review, and consequences should be legitimate and consistently administered.

Government employers, union workplaces, federally regulated employers, and organizations operating under a contract, grant, or licensing rule may have additional limits or mandatory procedures.

Written Policy and Consistent Administration

A written policy should identify prohibited conduct, covered workers, testing reasons, collection and laboratory procedures, refusals, confirmation, medical review, retesting, consequences, confidentiality, and any assistance options.

The policy matters directly in unemployment cases: Section 41-35-120(3) requires the company to have communicated a policy prohibiting illegal drug use and stating that a violation may result in termination.

State law: S.C. Code § 41-35-120(3)(a)(i)

Unemployment: Refusals and Positive Tests

Section 41-35-120(3) can disqualify a discharged worker until the worker obtains employment and earns at least eight times the weekly benefit amount when the employer proves the communicated policy and statutory conditions. Covered conduct includes refusing to provide or cooperate with a specimen request, providing an adulterated specimen, or a qualifying positive test for illegal drugs or legal drugs used unlawfully.

For a positive-test case, the specimen must be collected and labeled by an authorized person, tested by a laboratory certified by HHS/SAMHSA, the College of American Pathologists, or SLED, and confirmed by GC/MS or an approved equivalent or more accurate method.

State law: S.C. Code § 41-35-120(3)

Workers’ Compensation and Intoxication

South Carolina bars workers’ compensation when an injury or death was occasioned by the employee’s intoxication or willful intent to injure or kill. The party asserting the intoxication defense bears the burden of proof.

Because the statute focuses on whether intoxication occasioned the injury or death, employers should not describe a positive drug-test result by itself as automatically defeating a claim.

State law: S.C. Code § 42-9-60

State Contracts and Grants of $50,000 or More

Under South Carolina’s Drug-Free Workplace Act, a non-individual seeking a domestic state contract or grant valued at $50,000 or more must certify that it will provide a drug-free workplace. Required steps include a published prohibition and consequences, an awareness program, employee notice, workplace-conviction reporting, a response to qualifying convictions, and a good-faith compliance effort.

The Act does not itself say every covered contractor must drug test every employee; it establishes the listed workplace, notice, education, reporting, and response duties.

State law: S.C. Code §§ 44-107-30 to 44-107-50

Federal, Government, and Contract Rules

DOT-covered transportation testing must follow 49 CFR Part 40 and the applicable agency rule. Federal contractors and grantees may have duties under the federal Drug-Free Workplace Act, and government testing may raise constitutional, civil-service, or other public-employment requirements.

Collective-bargaining agreements, licensing rules, client contracts, and industry-specific requirements can also determine whether, when, and how testing occurs. Keep any federally mandated process distinct from a general non-DOT program.

Federal source: U.S. DOT — 49 CFR Part 40

Use results for the purpose the policy supports. A confirmed laboratory result, proof of present impairment, an unemployment determination, and a workers’ compensation causation decision are different questions. Document the testing reason and follow the procedure applicable to that decision.

Cannabis and Workplace Drug Testing in South Carolina

South Carolina has not legalized adult-use marijuana or established a broad medical-marijuana program. Its limited cannabidiol clinical-trial law, hemp products, lawful prescriptions, federal requirements, and the difference between a urine result and present impairment still require careful policy design.

Marijuana Remains Illegal Under State Law

The South Carolina Department of Public Health states that it is currently illegal in South Carolina to use or distribute marijuana. The state has not adopted general adult-use legalization or a broad dispensary-based medical-marijuana program.

Employers therefore are not operating under the applicant or employee cannabis protections found in some legalization states. Other employment laws, valid prescriptions, disability issues, federal requirements, contracts, and consistent policy administration still matter.

State source: South Carolina Department of Public Health — Hemp in Beverages

Julian’s Law Is Narrow

Julian’s Law concerns FDA-authorized cannabidiol clinical trials for qualifying patients with severe forms of epilepsy. The statute defines cannabidiol for this program as a finished preparation containing at least 98% cannabidiol and no more than 0.90% THC by volume.

This limited research framework is not a general medical-marijuana card program. Employers should evaluate any verified medication information through their normal confidential review process rather than assuming every cannabis-derived product has the same legal or testing status.

State law: S.C. Code §§ 44-53-1810 to 44-53-1840

Employers May Set Lawful THC Policies

A private employer generally may decide whether a non-DOT panel includes THC and may prohibit workplace possession, use, or impairment under a lawful and consistently administered policy. The policy should say whether a confirmed THC result is prohibited, which positions are covered, and what review and consequence process applies.

A urine THC result can reflect prior exposure and does not by itself establish when use occurred or whether the person is presently impaired. Separate the testing result from any impairment or accident-causation determination.

Hemp and CBD Products Can Create Risk

Hemp and marijuana are legally distinct, but South Carolina DPH explains that some hemp-infused products may contain THC. Product labels and marketing are not guarantees that use will never produce a positive marijuana metabolite result.

An employee’s explanation should be handled through the policy’s established review process. Employers should avoid promising that any retail CBD, delta-8, or hemp-derived product is “test safe.”

State source: South Carolina Department of Public Health — THC, CBD, and hemp information

Choose THC or no THC intentionally. A THC-inclusive test should match the employer’s written policy and the decision the result will support. No-THC panels are available when a non-DOT employer intentionally excludes marijuana. DOT testing remains subject to federal rules and includes marijuana.

DOT Drug Testing in South Carolina

South Carolina employers with employees performing federally regulated safety-sensitive transportation functions must follow the applicable federal DOT rules. The core procedural rule is 49 CFR Part 40, together with the regulations of the applicable DOT agency.

DOT Rules Are Separate from Non-DOT Testing

A personal or employer non-DOT drug test should not be substituted for a test that is required under DOT regulations. DOT programs have specific requirements for test reasons, forms, collection procedures, laboratories, Medical Review Officers, refusals, records, and return-to-duty processes.

Federal source: U.S. Department of Transportation — 49 CFR Part 40

Examples of DOT-Regulated Industries

  • Commercial motor carriers regulated by FMCSA.
  • Aviation employers regulated by FAA.
  • Railroad employers regulated by FRA.
  • Public transit employers regulated by FTA.
  • Pipeline operators regulated by PHMSA.
  • Other covered transportation operations under federal rules.

Drug Use and Overdose Data in South Carolina

CDC final 2024 mortality data provides statewide context for employers, individuals, policymakers, and safety programs. Population-level data should never be used to make assumptions about a particular person, workplace, city, county, or community.

1,467Drug overdose deaths in South CarolinaCDC final 2024 drug-overdose death count.
27.5Overdose death rate per 100,000CDC final 2024 age-adjusted drug-overdose mortality rate.

Official sources: CDC — Drug Overdose Mortality by State and CDC — South Carolina Stats of the States. All 2024 data shown by CDC on these pages is final.

South Carolina Drug Testing FAQ

Can private employers drug test applicants and employees in South Carolina?
Generally, yes. South Carolina does not have a single comprehensive statute that prescribes every private-sector drug-test procedure. Employers should use a written, job-related, consistently administered policy and comply with federal law, discrimination rules, contracts, collective-bargaining agreements, and any applicable public-sector requirements.
Can South Carolina employers require pre-employment drug testing?
Generally, yes. A private employer may make a job offer conditional on a negative test when the requirement is lawful and applied consistently to similarly situated applicants. Clear advance notice, documented chain of custody, laboratory confirmation, Medical Review Officer review, and confidential handling are prudent.
Can South Carolina employers use random, reasonable-suspicion, or post-accident testing?
Generally, a private employer may use those testing reasons when a lawful written policy authorizes them. Random selections should be neutral, reasonable-suspicion decisions should be based on contemporaneous objective facts, and post-accident criteria should be tied to legitimate safety concerns rather than automatic assumptions.
Does South Carolina require a written drug-testing policy?
No single statewide law expressly requires every private employer to maintain one for every non-DOT test. A clear written policy is still important and is specifically relevant to the unemployment statute, which requires the company to have communicated a policy prohibiting illegal drug use and warning that a violation may result in termination.
Can a positive drug test or refusal affect unemployment benefits in South Carolina?
Yes. Under S.C. Code § 41-35-120(3), a discharge for illegal drug use can disqualify a claimant until reemployment and earnings equal at least eight times the weekly benefit amount when the employer communicated the required policy and the statutory refusal or testing conditions are proved. Positive-test cases require authorized collection, a qualifying certified laboratory, and confirmation by GC/MS or an approved equivalent.
Can intoxication affect South Carolina workers’ compensation benefits?
Potentially. S.C. Code § 42-9-60 bars compensation when an injury or death was occasioned by the employee’s intoxication, and the party asserting that defense bears the burden of proof. A positive test alone should not be described as automatically deciding causation.
Do South Carolina state contractors have drug-free-workplace duties?
Yes, for covered awards. South Carolina’s Drug-Free Workplace Act requires a non-individual receiving a state grant or contract valued at $50,000 or more to certify a drug-free workplace and carry out specified notice, education, conviction-reporting, and response duties.
How does South Carolina’s marijuana law affect workplace testing?
South Carolina has not legalized adult-use marijuana or created a broad medical-marijuana program. Julian’s Law is limited to qualifying epilepsy patients and FDA-authorized cannabidiol clinical trials. Employers may maintain lawful THC policies, while still considering prescribed medications, disability law, federal rules, and consistent treatment.
Are DOT drug tests in South Carolina different from non-DOT tests?
Yes. DOT-regulated testing follows federal requirements, including 49 CFR Part 40. A personal or non-DOT employer test cannot replace a federally required DOT test.
What should I bring to a urine drug test in South Carolina?
Bring a valid photo ID and the Donor Pass issued for your order. Collection-site instructions and availability are shown during the ordering process after the case is created.
How long do urine drug-test results usually take?
Many negative laboratory urine results are available within roughly 1–2 business days after laboratory receipt. Confirmation or Medical Review Officer review can add several business days.

South Carolina and Federal Drug Testing Resources

We prioritize primary government sources for legal and public-health information and supplement them where useful. We periodically review this page for changes.

Ready to Order a Drug Test in South Carolina?

Choose your laboratory urine drug test, create the order, select an available collection site during checkout, and receive your Donor Pass.

This page is provided for general informational purposes and is not legal or medical advice. Drug-testing requirements can vary based on employer type, testing reason, industry, government status, collective-bargaining obligations, contracts, and federal or local requirements. Employers should consult qualified counsel before adopting or changing a testing policy. Public-health statistics are population-level estimates and should not be used to make assumptions about any individual or community.